UC held off a second half Seton Hall rally to improve to 6-3 in conference, the best Big East start in school history.
The Bearcats built a 20 point second half lead, but the Pirates rallied to within four. Sean Kilpatrick hit a clutch three-pointer and UC made enough foul shots down the stretch to beat Seton Hall, 65-59.
Kilpatrick led UC with 21 points.
UC improves to 18-4 overall on the season and the win is also Mick Cronin's 200th of his head coaching career.
UC's next game is Providence on Wednesday.